蓝布正提取物及其有效成分的药理作用研究进展
投稿时间:2026-04-16  修订日期:2026-05-07   点此下载全文
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作者中文名作者英文名单位中文名单位英文名E-Mail
庞建英 PANG Jianying 河北中医药大学 Hebei University of Chinese Medicine yjs20252140@hebcm.edu.cn 
董璐 DONG Lu 河北中医药大学 Hebei University of Chinese Medicine yjs20242128@hebcm.edu.cn 
陈旭 CHEN Xu 河北中医药大学 Hebei University of Chinese Medicine yjs20251012@hebcm.edu.cn 
张一昕 ZHANG Yixin 河北中医药大学 Hebei University of Chinese Medicine zhangyixin@hebcm.edu.cn 
郭龙 GUO Long 河北中医药大学 Hebei University of Chinese Medicine guolong@hebcm.edu.cn 
乐世俊* YUE Shijun 河北中医药大学 Hebei University of Chinese Medicine leshijun@hebcm.edu.cn 
基金项目:河北省自然科学基金项目(H2024423015);河北省省级科技计划项目(25292501D,246W2501D);河北省高等学校科学技术研究项目(QN2025158,QN2025094)
中文摘要:蓝布正为蔷薇科植物路边青Geum aleppicum Jacq.或柔毛路边青Geum japonicum Thunb. var. chinense Bolle的干燥全草,具有益气健脾,补血养阴,润肺化痰的功效,常用于治疗头痛头晕、小儿惊风、高血压、腰腿疼痛、月经不调等疾病。现代药理研究表明,蓝布正提取物及其有效成分(如鞣质类、黄酮类、三萜类、苯丙素类等)具有良好的心血管保护、抗凝血及造血、抗病原微生物、抗肿瘤、抗炎等多种作用。本文通过查阅国内外相关文献,对蓝布正提取物及其有效成分的药理作用的研究进展进行综述,以期为蓝布正的临床应用和药物研发提供参考依据。
中文关键词:蓝布正  鞣质类  药理作用  心血管保护  抗脑缺血再灌注损伤
 
Research progress on the pharmacological effects of Gei Herba extracts and active ingredients
Abstract:Gei Herba is the dried whole plant of Geum aleppicum Jacq.or Geum japonicum Thunb. var. chinense Bolle, which has the traditional efficacy of replenishing qi and invigorating spleen, nourishing blood and yin, moistening lung and resolving phlegm. It is often used to treat headache and dizziness, infantile convulsion, hypertension, lumbar and leg pain, irregular menstruation and other diseases. Modern pharmacological research shows that the extracts of Gei Herba and main chemical components (e.g., tannins, flavonoids, triterpenoids and phenylpropanoids)possess cardiovascular protection, anticoagulation and hematopoiesis, anti-pathogenic microorganism, anti-tumor, anti-inflammatory and other effects. In this review, the research progress of the pharmacological effects of Gei Herba extract and its active ingredients was reviewed by consulting relevant literature at home and abroad, in order to provide reference for the clinical application and drug research and development of Gei Herba.
keywords:Gei Herba  Tannins  Pharmacological effects  Cardiovascular protection  Anti-cerebral ischemia-reperfusion injury
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